THE westbound carriageway of the M62 near junction 32 at Castleford is closed following a three-vehicle collision in which a woman was killed.
A minibus, lorry and car were involved and it has been reported that several people were injured.
Yorkshire Ambulance Service has put major incident procedures into place and have sent out doctors and hazardous area response team.
The North West and Great North air ambulances are among emergency crews at the scene.
It is believed that the minibus was carrying a group of around 20 women who are all from the West Yorkshire area.
A spokesman for the Yorkshire Ambulance Service NHS Trust said: "Ambulance clinicians are providing treatment at the scene and are working closely with their emergency service colleagues.
"At this time the number of patients is unknown."
Motorists heading in that direction have been urged to use the M18 or M1 instead.
The carriageway is not expected to reopen until at least 6pm.
